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NOD2 Ligation Subverts IFNα Production by Liver Plasmacytoid Dendritic Cells and Inhibits Their T Cell Allostimulatory Activity Via B7-H1 Upregulation

Nucleotide-binding oligomerization domain (NOD)2/CARD15 protein, that senses muramyl dipeptide (MDP), a product of bacterial peptidoglycan, appears to play an important role in regulating intestinal immunity. Although the liver is exposed to gut-derived MDP, the influence of NOD2 ligation on hepatic...

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Detalhes bibliográficos
Main Authors: Castellaneta, Antonino, Sumpter, Tina L., Chen, Lieping, Tokita, Daisuke, Thomson, Angus W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786082/
https://ncbi.nlm.nih.gov/pubmed/19890047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900582
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