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Allostimulatory activity of BM-derived plasmacytoid DC is independent of IDO but regulated by ICOSL expression

We investigated the role of two key immunoregulatory molecules, indoleamine dioxygenase (IDO) and inducible costimulator ligand (ICOSL), in determining the function of bone marrow (BM)-derived plasmacytoid (p)DC, that offer potential for therapy of allograft rejection. pDC generated from BM of wild-...

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Bibliographic Details
Main Authors: Colvin, Bridget L., Sumpter, Tina L., Tokita, Daisuke, Salati, Jennifer, Mellor, Andrew L., Thomson, Angus W.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3721197/
https://ncbi.nlm.nih.gov/pubmed/19208362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.humimm.2009.01.021
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