Allostimulatory activity of BM-derived plasmacytoid DC is independent of IDO but regulated by ICOSL expression

We investigated the role of two key immunoregulatory molecules, indoleamine dioxygenase (IDO) and inducible costimulator ligand (ICOSL), in determining the function of bone marrow (BM)-derived plasmacytoid (p)DC, that offer potential for therapy of allograft rejection. pDC generated from BM of wild-...

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Hauptverfasser: Colvin, Bridget L., Sumpter, Tina L., Tokita, Daisuke, Salati, Jennifer, Mellor, Andrew L., Thomson, Angus W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3721197/
https://ncbi.nlm.nih.gov/pubmed/19208362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.humimm.2009.01.021
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