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Hepatic stellate cells undermine the allostimulatory function of liver myeloid dendritic cells via STAT3-dependent induction of IDO

Hepatic stellate cells (HSCs) are critical for hepatic wound repair and tissue remodeling. They also produce cytokines and chemokines that may contribute to the maintenance of hepatic immune homeostasis and the inherent tolerogenicity of the liver. The functional relationship between HSCs and the pr...

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Detalhes bibliográficos
Main Authors: Sumpter, Tina L., Dangi, Anil, Matta, Benjamin M., Huang, Chao, Stolz, Donna B., Vodovotz, Yoram, Thomson, Angus W., Gandhi, Chandrashekhar R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466356/
https://ncbi.nlm.nih.gov/pubmed/22962681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200819
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