Hepatic stellate cells undermine the allostimulatory function of liver myeloid dendritic cells via STAT3-dependent induction of IDO

Hepatic stellate cells (HSCs) are critical for hepatic wound repair and tissue remodeling. They also produce cytokines and chemokines that may contribute to the maintenance of hepatic immune homeostasis and the inherent tolerogenicity of the liver. The functional relationship between HSCs and the pr...

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Bibliographic Details
Main Authors: Sumpter, Tina L., Dangi, Anil, Matta, Benjamin M., Huang, Chao, Stolz, Donna B., Vodovotz, Yoram, Thomson, Angus W., Gandhi, Chandrashekhar R.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466356/
https://ncbi.nlm.nih.gov/pubmed/22962681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200819
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