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Origin and evolution of the adaptive immune system: genetic events and selective pressures
The adaptive immune system (AIS) in mammals, which is centred on lymphocytes bearing antigen receptors that are generated by somatic recombination, arose approximately 500 million years ago in jawed fish. This intricate defence system consists of many molecules, mechanisms and tissues that are not p...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3805090/ https://ncbi.nlm.nih.gov/pubmed/19997068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrg2703 |
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