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Reevaluation of the Immunological Big Bang: comparisons of two vertebrate adaptive immune systems
Classically the immunological ‘Big Bang’ of adaptive immunity was believed to have resulted from the insertion of a transposon into an immunoglobulin superfamily gene member, initiating RAG-based antigen receptor gene rearrangement in an ancestor of jawed vertebrates. However, the discovery of a sec...
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| Publicado no: | Curr Biol |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4354883/ https://ncbi.nlm.nih.gov/pubmed/25517375 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2014.09.070 |
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