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Origin and evolution of the specialized forms of proteasomes involved in antigen presentation

Proteasomes are a multi-subunit protease complex that produces peptides bound by major histocompatibility complex (MHC) class I molecules. Phylogenetic studies indicate tahat two specialized forms of proteasomes, immunoproteasomes and thymoproteasomes, and the proteasome activator PA28αβ emerged in...

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Dettagli Bibliografici
Pubblicato in:Immunogenetics
Autori principali: Kasahara, Masanori, Flajnik, Martin F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6377343/
https://ncbi.nlm.nih.gov/pubmed/30675634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00251-019-01105-0
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