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Enantioselective Total Synthesis of Guanacastepene N Using an Uncommon 7-Endo Heck Cyclization as a Pivotal Step

A convergent, enantioselective total synthesis of (+)-guanacastepene N was developed that features a 7-endo Heck cyclization as the key step. In the course of this synthesis, short syntheses of the enantiomerically pure cyclopentenone and cyclohexene building blocks 5 and 6, which constitute A and C...

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Bibliografiset tiedot
Päätekijät: Iimura, Shin, Overman, Larry E., Paulini, Ralph, Zakarian, Armen
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2006
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3804222/
https://ncbi.nlm.nih.gov/pubmed/17017789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja0650504
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