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WASH inhibits autophagy through suppression of Beclin 1 ubiquitination
Autophagy degrades cytoplasmic proteins and organelles to recycle cellular components that are required for cell survival and tissue homeostasis. However, it is not clear how autophagy is regulated in mammalian cells. WASH (Wiskott–Aldrich syndrome protein (WASP) and SCAR homologue) plays an essenti...
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| Main Authors: | , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
European Molecular Biology Organization
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3801434/ https://ncbi.nlm.nih.gov/pubmed/23974797 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.189 |
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