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WASH inhibits autophagy through suppression of Beclin 1 ubiquitination

Autophagy degrades cytoplasmic proteins and organelles to recycle cellular components that are required for cell survival and tissue homeostasis. However, it is not clear how autophagy is regulated in mammalian cells. WASH (Wiskott–Aldrich syndrome protein (WASP) and SCAR homologue) plays an essenti...

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Detalhes bibliográficos
Main Authors: Xia, Pengyan, Wang, Shuo, Du, Ying, Zhao, Zhenao, Shi, Lei, Sun, Lei, Huang, Guanling, Ye, Buqing, Li, Chong, Dai, Zhonghua, Hou, Ning, Cheng, Xuan, Sun, Qingyuan, Li, Lei, Yang, Xiao, Fan, Zusen
Formato: Artigo
Idioma:Inglês
Publicado em: European Molecular Biology Organization 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3801434/
https://ncbi.nlm.nih.gov/pubmed/23974797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.189
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