WASH inhibits autophagy through suppression of Beclin 1 ubiquitination

Autophagy degrades cytoplasmic proteins and organelles to recycle cellular components that are required for cell survival and tissue homeostasis. However, it is not clear how autophagy is regulated in mammalian cells. WASH (Wiskott–Aldrich syndrome protein (WASP) and SCAR homologue) plays an essenti...

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Bibliografiska uppgifter
Huvudupphovsmän: Xia, Pengyan, Wang, Shuo, Du, Ying, Zhao, Zhenao, Shi, Lei, Sun, Lei, Huang, Guanling, Ye, Buqing, Li, Chong, Dai, Zhonghua, Hou, Ning, Cheng, Xuan, Sun, Qingyuan, Li, Lei, Yang, Xiao, Fan, Zusen
Materialtyp: Artigo
Språk:Inglês
Publicerad: European Molecular Biology Organization 2013
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3801434/
https://ncbi.nlm.nih.gov/pubmed/23974797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.189
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