FoxO1-mediated autophagy is required for NK cell development and innate immunity

Natural killer (NK) cells exert a crucial role in early immune responses as a major innate effector component. However, the underlying mechanisms of NK cell development remain largely elusive. Here we show that robust autophagy appears in the stage of immature NK cells (iNKs), which is required for...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Wang, Shuo, Xia, Pengyan, Huang, Guanling, Zhu, Pingping, Liu, Jing, Ye, Buqing, Du, Ying, Fan, Zusen
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4820827/
https://ncbi.nlm.nih.gov/pubmed/27010363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11023
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