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FoxO1-mediated autophagy is required for NK cell development and innate immunity
Natural killer (NK) cells exert a crucial role in early immune responses as a major innate effector component. However, the underlying mechanisms of NK cell development remain largely elusive. Here we show that robust autophagy appears in the stage of immature NK cells (iNKs), which is required for...
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Publicado no: | Nat Commun |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4820827/ https://ncbi.nlm.nih.gov/pubmed/27010363 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11023 |
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