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FoxO1-mediated autophagy is required for NK cell development and innate immunity

Natural killer (NK) cells exert a crucial role in early immune responses as a major innate effector component. However, the underlying mechanisms of NK cell development remain largely elusive. Here we show that robust autophagy appears in the stage of immature NK cells (iNKs), which is required for...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Wang, Shuo, Xia, Pengyan, Huang, Guanling, Zhu, Pingping, Liu, Jing, Ye, Buqing, Du, Ying, Fan, Zusen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4820827/
https://ncbi.nlm.nih.gov/pubmed/27010363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11023
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