Experience-induced Arc/Arg3.1 primes CA1 pyramidal neurons for mGluR-dependent long-term synaptic depression

A novel experience induces Arc/Arg3.1 gene as well as plasticity of CA1 neural networks. To understand how these are linked, we briefly exposed GFP reporter mice of Arc transcription to a novel environment. Excitatory synaptic function of CA1 neurons with recent in vivo Arc-induction (ArcGFP+) was s...

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Bibliografiske detaljer
Main Authors:	Jakkamstti, Vikam, Tsai, Nien-Pei, Gross, Christina, Molinaro, Gemma, Collins, Katie A., Nicoletti, Ferdinando, Wang, Kuan H., Osten, Pavel, Bassell, Gary J., Gibson, Jay R., Huber, Kimberly M.
Format:	Artigo
Sprog:	Inglês
Udgivet:	2013
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3801421/ https://ncbi.nlm.nih.gov/pubmed/24094104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2013.07.020
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Experience-induced Arc/Arg3.1 primes CA1 pyramidal neurons for mGluR-dependent long-term synaptic depression

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