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Rapid translation of Arc/Arg3.1 selectively mediates mGluR dependent LTD through persistent increases in AMPAR endocytosis rate
Salient stimuli that modify behavior induce transcription of Activity regulated cytoskeleton-associated protein (Arc/Arg3.1) and transport Arc mRNA into dendrites, suggesting that local Arc translation mediates synaptic plasticity encoding such stimuli. Here we demonstrate that long-term synaptic de...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2580055/ https://ncbi.nlm.nih.gov/pubmed/18614031 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2008.05.014 |
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