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A role for dendritic mGluR5-mediated local translation of Arc/Arg3.1 in MEF2-dependent synapse elimination

Experience refines synaptic connectivity through neural activity-dependent regulation of transcription factors. Although activity-dependent regulation of transcription factors has been well described, it is unknown if synaptic activity and local, dendritic regulation of the induced transcripts are n...

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Hlavní autoři: Wilkerson, Julia R., Tsai, Nien-Pei, Maksimova, Marina A., Wu, Hao, Cabalo, Nicole P., Loerwald, Kristofer W., Dictenberg, Jason B., Gibson, Jay R., Huber, Kimberly M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4057996/
https://ncbi.nlm.nih.gov/pubmed/24857654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.04.035
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