Paracrine activation of WNT/β-catenin pathway in uterine leiomyoma stem cells promotes tumor growth

Uterine leiomyomas are extremely common estrogen and progesterone-dependent tumors of the myometrium and cause irregular uterine bleeding, severe anemia, and recurrent pregnancy loss in 15–30% of reproductive-age women. Each leiomyoma is thought to arise from a single mutated myometrial smooth muscl...

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Bibliografische gegevens
Hoofdauteurs: Ono, Masanori, Yin, Ping, Navarro, Antonia, Moravek, Molly B., Coon, John S., Druschitz, Stacy A., Serna, Vanida Ann, Qiang, Wenan, Brooks, David C., Malpani, Saurabh S., Ma, Jiajia, Ercan, Cihangir Mutlu, Mittal, Navdha, Monsivais, Diana, Dyson, Matthew T., Yemelyanov, Alex, Maruyama, Tetsuo, Chakravarti, Debabrata, Kim, J. Julie, Kurita, Takeshi, Gottardi, Cara J., Bulun, Serdar E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2013
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3801037/
https://ncbi.nlm.nih.gov/pubmed/24082114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1313650110
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