Inhibition of canonical WNT signaling attenuates human leiomyoma cell growth

OBJECTIVE: To assess the effect of three WNT/β-catenin pathway inhibitors—inhibitor of β-catenin and TCF4 (ICAT), niclosamide, and XAV939—on the proliferation of primary cultures of human uterine leiomyoma cells. DESIGN: Prospective study of human leiomyoma cells obtained from myomectomy or hysterec...

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Autors principals: Ono, Masanori, Yin, Ping, Navarro, Antonia, Moravek, Molly B., Coon V, John S., Druschitz, Stacy A., Gottardi, Cara J., Bulun, Serdar E.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Reproductive Medicine. Published by Elsevier Inc. 2014
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4008647/
https://ncbi.nlm.nih.gov/pubmed/24534281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fertnstert.2014.01.017
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