How allosteric control of Staphylococcus aureus penicillin binding protein 2a enables methicillin resistance and physiological function

The expression of penicillin binding protein 2a (PBP2a) is the basis for the broad clinical resistance to the β-lactam antibiotics by methicillin-resistant Staphylococcus aureus (MRSA). The high-molecular mass penicillin binding proteins of bacteria catalyze in separate domains the transglycosylase...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Otero, Lisandro H., Rojas-Altuve, Alzoray, Llarrull, Leticia I., Carrasco-López, Cesar, Kumarasiri, Malika, Lastochkin, Elena, Fishovitz, Jennifer, Dawley, Matthew, Hesek, Dusan, Lee, Mijoon, Johnson, Jarrod W., Fisher, Jed F., Chang, Mayland, Mobashery, Shahriar, Hermoso, Juan A.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2013
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3800995/
https://ncbi.nlm.nih.gov/pubmed/24085846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1300118110
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares