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Penicillin-Binding Protein 2a of Methicillin-Resistant Staphylococcus aureus

High-level resistance to β-lactam antibiotics in methicillin-resistant Staphylococcus aureus (MRSA) is due to expression of penicillin-binding protein 2a (PBP2a), a transpeptidase that catalyzes cell-wall crosslinking in the face of the challenge by β-lactam antibiotics. The activity of this protein...

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Bibliografiske detaljer
Udgivet i:IUBMB Life
Main Authors: Fishovitz, Jennifer, Hermoso, Juan A., Chang, Mayland, Mobashery, Shahriar
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4236225/
https://ncbi.nlm.nih.gov/pubmed/25044998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iub.1289
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