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An Antibody CDR3-Erythropoietin Fusion Protein
X-ray crystallographic analysis of a bovine antibody (BLV1H12) revealed a unique scaffold in its ultralong heavy chain complementarity determining region 3 (CDR3H) region that folds into a solvent exposed, antiparallel β-stranded “stalk” fused with a disulfide cross-linked “knob” domain. This unusua...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3800483/ https://ncbi.nlm.nih.gov/pubmed/23941200 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb4004749 |
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