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Alterations in Ryanodine Receptors and Related Proteins in Heart Failure
Sarcoplasmic reticulum (SR) Ca(2+) release plays an essential role in mediating cardiac myocyte contraction. Depolarization of the plasma membrane results in influx of Ca(2+) through L-type Ca(2+) channels (LTCCs) that in turn triggers efflux of Ca(2+) from the SR through ryanodine receptor type-2 c...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3800473/ https://ncbi.nlm.nih.gov/pubmed/23770282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2013.06.008 |
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