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Switchable reporter enzymes based on mutually exclusive domain interactions allow antibody detection directly in solution

Detection of antibodies is essential for the diagnosis of many diseases including infections, allergies and autoimmune diseases. Current heterogeneous immunoassays require multiple time-consuming binding and washing steps, which limits their application in point-of-care diagnostics and high-throughp...

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Bibliografski detalji
Glavni autori: Banala, Sambashiva, Aper, Stijn J.A., Schalk, Werner, Merkx, Maarten
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3800467/
https://ncbi.nlm.nih.gov/pubmed/23941162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb400406x
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