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Switchable reporter enzymes based on mutually exclusive domain interactions allow antibody detection directly in solution

Detection of antibodies is essential for the diagnosis of many diseases including infections, allergies and autoimmune diseases. Current heterogeneous immunoassays require multiple time-consuming binding and washing steps, which limits their application in point-of-care diagnostics and high-throughp...

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Detalhes bibliográficos
Main Authors: Banala, Sambashiva, Aper, Stijn J.A., Schalk, Werner, Merkx, Maarten
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3800467/
https://ncbi.nlm.nih.gov/pubmed/23941162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb400406x
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