The Timing of Myocardial Trpm7 Deletion during Cardiogenesis Variably Disrupts Adult Ventricular Function, Conduction and Repolarization

BACKGROUND: Transient Receptor Potential (TRP) channels are a superfamily of broadly expressed ion channels with diverse physiological roles. TRPC1, 3 and 6 are believed to contribute to cardiac hypertrophy in mouse models. Human mutations in TRPM4 have been linked to progressive familial heart bloc...

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Autores principales: Sah, Rajan, Mesirca, Pietro, Mason, Xenos, Gibson, William, Bates-Withers, Christopher, Van den Boogert, Marjolein, Chaudhuri, Dipayan, Pu, William, Mangoni, Matteo E., Clapham, David E.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3800036/
https://ncbi.nlm.nih.gov/pubmed/23734001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.112.000768
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