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Potent norovirus inhibitors based on the acyclic sulfamide scaffold

The development of small molecule therapeutics to combat norovirus infection is of considerable interest from a public health perspective because of the highly contagious nature of noroviruses. A series of amino acid-derived acyclic sulfamide-based norovirus inhibitors has been synthesized and evalu...

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Detalhes bibliográficos
Main Authors: Dou, Dengfeng, Tiew, Kok-Chuan, Rao Mandadapu, Sivakoteswara, Reddy Gunnam, Mallikarjuna, Alliston, Kevin R., Kim, Yunjeong, Chang, Kyeong-Ok, Groutas, William C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799806/
https://ncbi.nlm.nih.gov/pubmed/22356738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2012.01.030
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