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Integrative analysis revealed the molecular mechanism underlying RBM10-mediated splicing regulation

RBM10 encodes an RNA binding protein. Mutations in RBM10 are known to cause multiple congenital anomaly syndrome in male humans, the TARP syndrome. However, the molecular function of RBM10 is unknown. Here we used PAR-CLIP to identify thousands of binding sites of RBM10 and observed significant RBM1...

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Detalhes bibliográficos
Main Authors: Wang, Yongbo, Gogol-Döring, Andreas, Hu, Hao, Fröhler, Sebastian, Ma, Yunxia, Jens, Marvin, Maaskola, Jonas, Murakawa, Yasuhiro, Quedenau, Claudia, Landthaler, Markus, Kalscheuer, Vera, Wieczorek, Dagmar, Wang, Yang, Hu, Yuhui, Chen, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799496/
https://ncbi.nlm.nih.gov/pubmed/24000153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201302663
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