Mechanism of E-cadherin dimerization probed by NMR relaxation dispersion

Epithelial cadherin (E-cadherin), a member of the classical cadherin family, mediates calcium-dependent homophilic cell–cell adhesion. Crystal structures of classical cadherins reveal an adhesive dimer interface featuring reciprocal exchange of N-terminal β-strands between two protomers. Previous wo...

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Main Authors: Li, Ying, Altorelli, Nicole L., Bahna, Fabiana, Honig, Barry, Shapiro, Lawrence, Palmer, Arthur G.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2013
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799306/
https://ncbi.nlm.nih.gov/pubmed/24067646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1314303110
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