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Essential role of PR-domain protein MDS1-EVI1 in MLL-AF9 leukemia
A subgroup of leukemogenic mixed-lineage leukemia (MLL) fusion proteins (MFPs) including MLL-AF9 activates the Mecom locus and exhibits extremely poor clinical prognosis. Mecom encodes EVI1 and MDS1-EVI1 (ME) proteins via alternative transcription start sites; these differ by the presence of a PRDI-...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society of Hematology
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3799001/ https://ncbi.nlm.nih.gov/pubmed/24021671 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-08-453662 |
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