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D-512 and D-440 as Novel Multifunctional Dopamine Agonists: Characterization of Neuroprotection Properties and Evaluation of In Vivo Efficacy in a Parkinson’s Disease Animal Model
[Image: see text] In this Article, we have demonstrated the in vivo efficacy of D-512 and D-440 in a 6-OHDA-induced unilaterally lesioned rat model experiment, a Parkinson’s disease animal model. D-512 is a novel highly potent D2/D3 agonist, and D-440 is a novel highly selective D3 agonist. We evalu...
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| Main Authors: | , , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American
Chemical Society
2013
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3798991/ https://ncbi.nlm.nih.gov/pubmed/23906010 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn400106n |
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