Triple reuptake inhibitors as potential next-generation antidepressants: a new hope?

Por Sharma, Horrick, Santra, Soumava, Dutta, Aloke
Publicado no Future Med Chem (2015)

Interaction of D(3) preferring agonist (−)-N(6)-(2-(4-(Biphenyl-4-yl)piperazin-1-yl)ethyl)-N(6)-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine (D-264) with cloned human D(2L...

Por Kuzhikandathil, Eldo V., Cote, Samantha, Santra, Soumava, Dutta, Aloke K.
Publicado em 2012

D-512 and D-440 as Novel Multifunctional Dopamine Agonists: Characterization of Neuroprotection Properties and Evaluation of In Vivo Efficacy in a Parkinson’s Disease Animal Model...

Por Santra, Soumava, Xu, Liping, Shah, Mrudang, Johnson, Mark, Dutta, Aloke
Publicado em 2013

Flexible and biomimetic analogs of triple uptake inhibitor 4-((((3S,6S)-6-benzhydryltetrahydro-2H-pyran-3-yl)amino)methyl)phenol : Synthesis, biological characterization, and devel...

Por Sharma, Horrick, Santra, Soumava, Debnath, Joy, Antonio, Tamara, Reith, Maarten, Dutta, Aloke
Publicado em 2013

Development of potent dopamine-norepinephrine uptake inhibitors (DNRIs) based on a (2S,4R,5R)-2-benzhydryl-5-((4-methoxybenzyl)amino)tetrahydro-2H-pyran-4-ol molecular template

Por Santra, Soumava, Sharma, Horrick, Vedachalam, Seenuvasan, Antonio, Tamara, Reith, Maarten, Dutta, Aloke
Publicado no Bioorg Med Chem (2014)

Structural Exploration of (3S,6S)-6-Benzhydryl-N-benzyltetrahydro-2H-pyran-3-amine Analogues: Identification of Potent Triple Monoamine Reuptake Inhibitors as Potential Antidepress...

Por Santra, Soumava, Gogoi, Sanjib, Gopishetty, Bhaskar, Antonio, Tamara, Zhen, Juan, Reith, Maarten E. A., Dutta, Aloke K.
Publicado em 2012

Further structure-activity relationship studies on 4-((((3S,6S)-6-benzhydryltetrahydro-2H-pyran-3-yl)amino)methyl)phenol: Identification of compounds with triple uptake inhibitory...

Por Gopishetty, Bhaskar, Hazeldine, Stuart, Santra, Soumava, Johnson, Mark, Modi, Gyan, Ali, Solav, Zhen, Juan, Reith, Maarten, Dutta, Aloke
Publicado em 2011

Pharmacological and Behavioral Characterization of D-473, an Orally Active Triple Reuptake Inhibitor Targeting Dopamine, Serotonin and Norepinephrine Transporters

Por Dutta, Aloke K., Santra, Soumava, Sharma, Horrick, Voshavar, Chandrashekhar, Xu, Liping, Mabrouk, Omar, Antonio, Tamara, Reith, Maarten E. A.
Publicado no PLoS One (2014)