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Further structure-activity relationship studies on 4-((((3S,6S)-6-benzhydryltetrahydro-2H-pyran-3-yl)amino)methyl)phenol: Identification of compounds with triple uptake inhibitory activity as potential antidepressant agents

To investigate structural alterations of the lead triple uptake inhibitor molecule, disubstituted 4-((((3S,6S)-6-benzhydryltetrahydro-2H-pyran-3-yl)amino)methyl)phenol, we have carried out structure-activity relationship (SAR) studies to investigate the effect of alteration of aromatic substitutions...

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Hlavní autoři: Gopishetty, Bhaskar, Hazeldine, Stuart, Santra, Soumava, Johnson, Mark, Modi, Gyan, Ali, Solav, Zhen, Juan, Reith, Maarten, Dutta, Aloke
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3085959/
https://ncbi.nlm.nih.gov/pubmed/21446715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm200020a
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