PICT1 regulates TP53 via RPL11 and is involved in gastric cancer progression

BACKGROUND: The TP53 pathway is frequently inactivated in human cancers. PICT1 (also known as GLTSCR2) is a novel regulator of the MDM2-TP53 pathway via its interaction with the ribosomal protein RPL11 in the nucleolus. However, the clinical significance of PICT1 in gastric cancer remains unknown. M...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Uchi, R, Kogo, R, Kawahara, K, Sudo, T, Yokobori, T, Eguchi, H, Sugimachi, K, Maehama, T, Mori, M, Suzuki, A, Komune, S, Mimori, K
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2013
Sujets:
Molecular Diagnostics
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798961/
https://ncbi.nlm.nih.gov/pubmed/24045667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.561
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