Regulation of the MDM2-P53 pathway and tumor growth by PICT1 via nucleolar RPL11

PICT1 (also known as GLTSCR2) is considered a tumor suppressor because it stabilizes phosphatase and tensin homolog (PTEN), but individuals with oligodendrogliomas lacking chromosome 19q13, where PICT1 is located, have better prognoses than other oligodendroglioma patients. To clarify the function o...

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Veröffentlicht in:Nat Med
Hauptverfasser: Sasaki, Masato, Kawahara, Kohichi, Nishio, Miki, Mimori, Koshi, Kogo, Ryunosuke, Hamada, Koichi, Itoh, Bunsho, Wang, Jia, Komatsu, Yukako, Yang, Yong Ryoul, Hikasa, Hiroki, Horie, Yasuo, Yamashita, Takayuki, Kamijo, Takehiko, Zhang, Yanping, Zhu, Yan, Prives, Carol, Nakano, Toru, Mak, Tak Wah, Sasaki, Takehiko, Maehama, Tomohiko, Mori, Masaki, Suzuki, Akira
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4578312/
https://ncbi.nlm.nih.gov/pubmed/21804542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2392
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