Unique volatolomic signatures of TP53 and KRAS in lung cells

BACKGROUND: Volatile organic compounds (VOCs) are potential biomarkers for cancer detection in breath, but it is unclear if they reflect specific mutations. To test this, we have compared human bronchial epithelial cell (HBEC) cell lines carrying the KRAS(V12) mutation, knockdown of TP53 or both wit...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Davies, M P A, Barash, O, Jeries, R, Peled, N, Ilouze, M, Hyde, R, Marcus, M W, Field, J K, Haick, H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4453850/
https://ncbi.nlm.nih.gov/pubmed/25051409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.411
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