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Unique volatolomic signatures of TP53 and KRAS in lung cells

BACKGROUND: Volatile organic compounds (VOCs) are potential biomarkers for cancer detection in breath, but it is unclear if they reflect specific mutations. To test this, we have compared human bronchial epithelial cell (HBEC) cell lines carrying the KRAS(V12) mutation, knockdown of TP53 or both wit...

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Bibliografische gegevens
Gepubliceerd in:Br J Cancer
Hoofdauteurs: Davies, M P A, Barash, O, Jeries, R, Peled, N, Ilouze, M, Hyde, R, Marcus, M W, Field, J K, Haick, H
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4453850/
https://ncbi.nlm.nih.gov/pubmed/25051409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.411
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