Amplification of PVT-1 is involved in poor prognosis via apoptosis inhibition in colorectal cancers

BACKGROUND: We previously conducted gene expression microarray analyses to identify novel indicators for colorectal cancer (CRC) metastasis and prognosis from which we identified PVT-1 as a candidate gene. PVT-1, which encodes a long noncoding RNA, mapped to chromosome 8q24 whose copy-number amplifi...

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Hlavní autoři: Takahashi, Y, Sawada, G, Kurashige, J, Uchi, R, Matsumura, T, Ueo, H, Takano, Y, Eguchi, H, Sudo, T, Sugimachi, K, Yamamoto, H, Doki, Y, Mori, M, Mimori, K
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2014
Témata:
Molecular Diagnostics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887297/
https://ncbi.nlm.nih.gov/pubmed/24196785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.698
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