Age-related increases in ozone-induced injury and altered pulmonary mechanics in mice with progressive lung inflammation

In these studies we determined whether progressive pulmonary inflammation associated with aging in surfactant protein D (Sftpd)(−/−) mice leads to an exacerbated response to ozone. In Sftpd(−/−) mice, but not wild-type (WT) mice, age-related increases in numbers of enlarged vacuolated macrophages we...

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Hlavní autoři: Groves, Angela M., Gow, Andrew J., Massa, Christopher B., Hall, LeRoy, Laskin, Jeffrey D., Laskin, Debra L.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798776/
https://ncbi.nlm.nih.gov/pubmed/23997172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00027.2013
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