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Epimorphin deletion inhibits polyposis in the Apc(min/+) mouse model of colon carcinogenesis via decreased myofibroblast HGF secretion

Interactions between the epithelium and surrounding mesenchyme/stroma play an important role in normal gut morphogenesis, the epithelial response to injury, and epithelial carcinogenesis. The tumor microenvironment, composed of stromal cells including myofibroblasts and immune cells, regulates tumor...

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Autors principals: Swietlicki, Elzbieta A., Bala, Shashi, Lu, Jianyun, Shaker, Anisa, Kularatna, Gowri, Levin, Marc S., Rubin, Deborah C.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798733/
https://ncbi.nlm.nih.gov/pubmed/23886856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00486.2012
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