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Epimorphin deletion inhibits polyposis in the Apc(min/+) mouse model of colon carcinogenesis via decreased myofibroblast HGF secretion

Interactions between the epithelium and surrounding mesenchyme/stroma play an important role in normal gut morphogenesis, the epithelial response to injury, and epithelial carcinogenesis. The tumor microenvironment, composed of stromal cells including myofibroblasts and immune cells, regulates tumor...

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書誌詳細
主要な著者: Swietlicki, Elzbieta A., Bala, Shashi, Lu, Jianyun, Shaker, Anisa, Kularatna, Gowri, Levin, Marc S., Rubin, Deborah C.
フォーマット: Artigo
言語:Inglês
出版事項: American Physiological Society 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798733/
https://ncbi.nlm.nih.gov/pubmed/23886856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00486.2012
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