Cargando...

Drug Rescue Distinguishes between Different Structural Models of Human P-Glycoprotein

[Image: see text] There is no high-resolution crystal structure of the human P-glycoprotein (P-gp) drug pump. Homology models of human P-gp based on the crystal structures of mouse or Caenorhabditis elegans P-gps show large differences in the orientation of transmembrane segment 5 (TM5). TM5 is one...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Loo, Tip W., Clarke, David M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Chemical Society 2013
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798097/
https://ncbi.nlm.nih.gov/pubmed/24083983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi401269m
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!