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Transmembrane segment 7 of human P-glycoprotein forms part of the drug-binding pocket

P-gp (P-glycoprotein; ABCB1) protects us by transporting a broad range of structurally unrelated compounds out of the cell. Identifying the regions of P-gp that make up the drug-binding pocket is important for understanding the mechanism of transport. The common drug-binding pocket is at the interfa...

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Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Loo, Tip W., Bartlett, M. Claire, Clarke, David M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Portland Press Ltd. 2006
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1609921/
https://ncbi.nlm.nih.gov/pubmed/16813563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060715
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