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Transmembrane segment 7 of human P-glycoprotein forms part of the drug-binding pocket
P-gp (P-glycoprotein; ABCB1) protects us by transporting a broad range of structurally unrelated compounds out of the cell. Identifying the regions of P-gp that make up the drug-binding pocket is important for understanding the mechanism of transport. The common drug-binding pocket is at the interfa...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Portland Press Ltd.
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1609921/ https://ncbi.nlm.nih.gov/pubmed/16813563 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060715 |
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