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Sculpting MHC class II-restricted self and non-self peptidome by the class I antigen-processing machinery and its impact on CD4(+) TCR repertoire and Th cell responses
It is generally assumed that the MHC class I antigen (Ag)-processing (CAP) machinery —which supplies peptides for presentation by class I molecules— plays no role in class II-restricted presentation of cytoplasmic Ags. In striking contrast to this assumption, we previously reported that proteasome i...
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Main Authors: | , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3798073/ https://ncbi.nlm.nih.gov/pubmed/23386199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201243087 |
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