Caricamento...
A Newly Identified Pirh2 substrate SCYL1-BP1 can bind to MDM2 and accelerate MDM2 self-ubiquitination
The SCYL1-BP1 protein was identified as an interacting partner of E3 ligase Pirh2 and MDM2 by yeast two-hybrid screening. Further investigation suggested there are two interactions involved in different mechanisms. SCYL1-BP1 can be ubiquitinated and degraded by Pirh2 but not by MDM2, which suggests...
Salvato in:
| Autori principali: | , , , , , |
|---|---|
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3798065/ https://ncbi.nlm.nih.gov/pubmed/20598683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2010.06.027 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|