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Identification of Pirh2D, an Additional Novel Isoform of Pirh2 Ubiquitin Ligase

Pirh2 is an E3 ubiquitin ligase that promotes tumor suppressor p53 ubiquitination and proteasomal degradation. Recently, we have reported the identification and characterization of two novel isoforms of Pirh2 named Pirh2B and Pirh2C and accordingly, reclassified the full-length Pirh2 as Pirh2A. Both...

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Autori principali: Shi, Jingxue, Huang, Ying, Sheikh, M. Saeed
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847410/
https://ncbi.nlm.nih.gov/pubmed/20357911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4255/mcpharmacol.10.04
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