Regulation of the Expression of Chaperone gp96 in Macrophages and Dendritic Cells

The chaperone function of the ER-residing heat shock protein gp96 plays an important role in protein physiology and has additionally important immunological functions due to its peptide-binding capacity. Low amounts of gp96 stimulate immunity; high quantities induce tolerance by mechanisms not fully...

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Autors principals: Wolfram, Lutz, Fischbeck, Anne, Frey-Wagner, Isabelle, Wojtal, Kacper A., Lang, Silvia, Fried, Michael, Vavricka, Stephan R., Hausmann, Martin, Rogler, Gerhard
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3797789/
https://ncbi.nlm.nih.gov/pubmed/24146856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076350
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