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Glycoprotein (gp) 96 expression: induced during differentiation of intestinal macrophages but impaired in Crohn’s disease

Background: The glycoprotein (gp) 96 links the adaptive with the innate immune system. It is a chaperone with a binding domain for peptides generated by proteasomal degradation. During cellular stress, peptide loaded gp96 can be released and presented to T cells by antigen presenting cells (APCs). M...

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Detalhes bibliográficos
Main Authors: Schreiter, K, Hausmann, M, Spoettl, T, Strauch, U G, Bataille, F, Schoelmerich, J, Herfarth, H, Falk, W, Rogler, G
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2005 by Gut 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1774602/
https://ncbi.nlm.nih.gov/pubmed/15951537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2004.053116
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