Cathepsins B, L and D in inflammatory bowel disease macrophages and potential therapeutic effects of cathepsin inhibition in vivo

The cathepsins D (CTSD), B (CTSB) and L (CTSL) are important for the intracellular degradation of proteins. Increased cathepsin expression is associated with inflammatory diseases. We have shown previously an induction of CTSD expression in intestinal macrophages (IMAC) in inflamed mucosa of patient...

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Bibliografiske detaljer
Main Authors: Menzel, K, Hausmann, M, Obermeier, F, Schreiter, K, Dunger, N, Bataille, F, Falk, W, Scholmerich, J, Herfarth, H, Rogler, G
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2006
Fag:
Basic Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1809720/
https://ncbi.nlm.nih.gov/pubmed/16968411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2006.03188.x
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