Cathepsins B, L and D in inflammatory bowel disease macrophages and potential therapeutic effects of cathepsin inhibition in vivo

The cathepsins D (CTSD), B (CTSB) and L (CTSL) are important for the intracellular degradation of proteins. Increased cathepsin expression is associated with inflammatory diseases. We have shown previously an induction of CTSD expression in intestinal macrophages (IMAC) in inflamed mucosa of patient...

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Bibliographische Detailangaben
Hauptverfasser: Menzel, K, Hausmann, M, Obermeier, F, Schreiter, K, Dunger, N, Bataille, F, Falk, W, Scholmerich, J, Herfarth, H, Rogler, G
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 2006
Schlagworte:
Basic Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1809720/
https://ncbi.nlm.nih.gov/pubmed/16968411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2006.03188.x
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