Cathepsins B, L and D in inflammatory bowel disease macrophages and potential therapeutic effects of cathepsin inhibition in vivo

The cathepsins D (CTSD), B (CTSB) and L (CTSL) are important for the intracellular degradation of proteins. Increased cathepsin expression is associated with inflammatory diseases. We have shown previously an induction of CTSD expression in intestinal macrophages (IMAC) in inflamed mucosa of patient...

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Detalhes bibliográficos
Main Authors: Menzel, K, Hausmann, M, Obermeier, F, Schreiter, K, Dunger, N, Bataille, F, Falk, W, Scholmerich, J, Herfarth, H, Rogler, G
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2006
Assuntos:
Basic Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1809720/
https://ncbi.nlm.nih.gov/pubmed/16968411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2006.03188.x
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