Targeted Gene Deletion of miRNAs in Mice by TALEN System

Mice are among the most valuable model animal species with an enormous amount of heritage in genetic modification studies. However, targeting genes in mice is sometimes difficult, especially for small genes, such as microRNAs (miRNAs) and targeting genes in repeat sequences. Here we optimized the ap...

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Detalhes bibliográficos
Main Authors: Takada, Shuji, Sato, Tempei, Ito, Yoshiaki, Yamashita, Satoshi, Kato, Tomoko, Kawasumi, Miyuri, Kanai-Azuma, Masami, Igarashi, Arisa, Kato, Tomomi, Tamano, Moe, Asahara, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3797721/
https://ncbi.nlm.nih.gov/pubmed/24146809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076004
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