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Mapping of a responsible region for sex reversal upstream of Sox9 by production of mice with serial deletion in a genomic locus
Sox9 plays critical roles in testis formation. By mapping four familial cases of disorders of sexual development, a 32.5 kb sequence located far upstream of SOX9 was previously identified as being a commonly deleted region and named the XY sex reversal region (XYSR). To narrow down a responsible seq...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6269501/ https://ncbi.nlm.nih.gov/pubmed/30504911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-35746-0 |
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