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Deletion of conserved sequences in IG-DMR at Dlk1-Gtl2 locus suggests their involvement in expression of paternally expressed genes in mice

Expression regulation of the Dlk1-Dio3 imprinted domain by the intergenic differentially methylated region (IG-DMR) is essential for normal embryonic development in mammals. In this study, we investigated conserved IG-DMR genomic sequences in eutherians to elucidate their role in genomic imprinting...

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Detalhes bibliográficos
Publicado no:J Reprod Dev
Main Authors: SAITO, Takeshi, HARA, Satoshi, TAMANO, Moe, ASAHARA, Hiroshi, TAKADA, Shuji
Formato: Artigo
Idioma:Inglês
Publicado em: The Society for Reproduction and Development 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5320436/
https://ncbi.nlm.nih.gov/pubmed/27904015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1262/jrd.2016-135
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