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Phosphorylated Phospholamban Stabilizes a Compact Conformation of the Cardiac Calcium-ATPase
The sarcoendoplasmic reticulum calcium ATPase (SERCA) plays a key role in cardiac calcium handling and is considered a high-value target for the treatment of heart failure. SERCA undergoes conformational changes as it harnesses the chemical energy of ATP for active transport. X-ray crystallography h...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Biophysical Society
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3797577/ https://ncbi.nlm.nih.gov/pubmed/24138857 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.08.045 |
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