α(2)δ-1 Gene Deletion Affects Somatosensory Neuron Function and Delays Mechanical Hypersensitivity in Response to Peripheral Nerve Damage

The α(2)δ-1 subunit of voltage-gated calcium channels is upregulated after sensory nerve injury and is also the therapeutic target of gabapentinoid drugs. It is therefore likely to play a key role in the development of neuropathic pain. In this study, we have examined mice in which α(2)δ-1 gene expr...

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Bibliografiske detaljer
Main Authors: Patel, Ryan, Bauer, Claudia S., Nieto-Rostro, Manuela, Margas, Wojciech, Ferron, Laurent, Chaggar, Kanchan, Crews, Kasumi, Ramirez, Juan D., Bennett, David L. H., Schwartz, Arnold, Dickenson, Anthony H., Dolphin, Annette C.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2013
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3797367/
https://ncbi.nlm.nih.gov/pubmed/24133248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1026-13.2013
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