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Genome instability and embryonic developmental defects in RMI1 deficient mice
RMI1 forms an evolutionarily conserved complex with BLM/TOP3α/RMI2 (BTR complex) to prevent and resolve aberrant recombination products, thereby promoting genome stability. Most of our knowledge about RMI1 function has been obtained from biochemical studies in vitro. In contrast, the role of RMI1 in...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3797188/ https://ncbi.nlm.nih.gov/pubmed/23900276 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2013.07.004 |
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